I think it's just the eye piece of Spidey's suit that are CGI, the rest is real. I think it looks kind of CGI because it is so much more colorful that most of the other Marvel characters suits.
THIS. It sets it apart from the last two big screen versions of Spider-Man by allowing him to express emotion thru the mask ala the comics. Hoping that it will finally stop the worn out "heroes running around without their masks" routine that gets played out in various comic movies.
Makes sense Spider-Man would look so out of place considering he's just a kid and he doesn't know much about being subtle.